| Title |
Isolation of HIV-1-Neutralizing Mucosal Monoclonal Antibodies from Human Colostrum
|
|---|---|
| Published in |
PLOS ONE, May 2012
|
| DOI | 10.1371/journal.pone.0037648 |
| Pubmed ID | |
| Authors |
James Friedman, S. Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, Genevieve G. Fouda, Guang Yang, Garnett Kelsoe, Guido Ferrari, Georgia D. Tomaras, Barton F. Haynes, Hua-Xin Liao, M. Anthony Moody, Sallie R. Permar |
| Abstract |
Generation of potent anti-HIV antibody responses in mucosal compartments is a potential requirement of a transmission-blocking HIV vaccine. HIV-specific, functional antibody responses are present in breast milk, and these mucosal antibody responses may play a role in protection of the majority of HIV-exposed, breastfeeding infants. Therefore, characterization of HIV-specific antibodies produced by B cells in milk could guide the development of vaccines that elicit protective mucosal antibody responses. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 31% |
| Canada | 2 | 15% |
| United Kingdom | 1 | 8% |
| Panama | 1 | 8% |
| Mexico | 1 | 8% |
| Colombia | 1 | 8% |
| Unknown | 3 | 23% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 69% |
| Practitioners (doctors, other healthcare professionals) | 2 | 15% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 2% |
| Unknown | 43 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 30% |
| Researcher | 10 | 23% |
| Student > Bachelor | 5 | 11% |
| Other | 4 | 9% |
| Student > Doctoral Student | 2 | 5% |
| Other | 4 | 9% |
| Unknown | 6 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 45% |
| Immunology and Microbiology | 6 | 14% |
| Medicine and Dentistry | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Sports and Recreations | 3 | 7% |
| Other | 2 | 5% |
| Unknown | 7 | 16% |