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Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-Mediated Reprogramming

Overview of attention for article published in PLOS ONE, May 2012
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Title
Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-Mediated Reprogramming
Published in
PLOS ONE, May 2012
DOI 10.1371/journal.pone.0037055
Pubmed ID
Authors

Nathalie Swales, Geert A. Martens, Stefan Bonné, Yves Heremans, Rehannah Borup, Mark Van de Casteele, Zhidong Ling, Daniel Pipeleers, Philippe Ravassard, Finn Nielsen, Jorge Ferrer, Harry Heimberg

Abstract

Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to improve it.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 1%
Germany 1 1%
Belgium 1 1%
Unknown 75 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 26%
Researcher 17 22%
Student > Master 11 14%
Student > Postgraduate 6 8%
Student > Bachelor 5 6%
Other 13 17%
Unknown 6 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 31%
Biochemistry, Genetics and Molecular Biology 24 31%
Medicine and Dentistry 14 18%
Chemistry 3 4%
Neuroscience 2 3%
Other 3 4%
Unknown 8 10%