| Title |
Type I Interferons Are Associated with Subclinical Markers of Cardiovascular Disease in a Cohort of Systemic Lupus Erythematosus Patients
|
|---|---|
| Published in |
PLOS ONE, May 2012
|
| DOI | 10.1371/journal.pone.0037000 |
| Pubmed ID | |
| Authors |
Emily C. Somers, Wenpu Zhao, Emily E. Lewis, Lu Wang, Jeffrey J. Wing, Baskaran Sundaram, Ella A. Kazerooni, W. Joseph McCune, Mariana J. Kaplan |
| Abstract |
Systemic lupus erythematosus (SLE) patients have a striking increase in cardiovascular (CV) comorbidity not fully explained by the Framingham risk score. Recent evidence from in vitro studies suggests that type I interferons (IFN) could promote premature CV disease (CVD) in SLE. We assessed the association of type I IFN signatures with functional and anatomical evidence of vascular damage, and with biomarkers of CV risk in a cohort of lupus patients without overt CVD. |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Greece | 1 | 1% |
| Poland | 1 | 1% |
| Unknown | 90 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 20% |
| Student > Master | 16 | 17% |
| Student > Ph. D. Student | 10 | 11% |
| Student > Bachelor | 8 | 8% |
| Other | 7 | 7% |
| Other | 20 | 21% |
| Unknown | 15 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 49 | 52% |
| Immunology and Microbiology | 6 | 6% |
| Agricultural and Biological Sciences | 5 | 5% |
| Biochemistry, Genetics and Molecular Biology | 4 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 9 | 9% |
| Unknown | 19 | 20% |