Title |
Overfeeding Reduces Insulin Sensitivity and Increases Oxidative Stress, without Altering Markers of Mitochondrial Content and Function in Humans
|
---|---|
Published in |
PLOS ONE, May 2012
|
DOI | 10.1371/journal.pone.0036320 |
Pubmed ID | |
Authors |
Dorit Samocha-Bonet, Lesley V. Campbell, Trevor A. Mori, Kevin D. Croft, Jerry R. Greenfield, Nigel Turner, Leonie K. Heilbronn |
Abstract |
Mitochondrial dysfunction and increased oxidative stress are associated with obesity and type 2 diabetes. High fat feeding induces insulin resistance and increases skeletal muscle oxidative stress in rodents, but there is controversy as to whether skeletal muscle mitochondrial biogenesis and function is altered. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 20% |
Comoros | 1 | 10% |
Taiwan | 1 | 10% |
Hungary | 1 | 10% |
United States | 1 | 10% |
Australia | 1 | 10% |
Unknown | 3 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 70% |
Practitioners (doctors, other healthcare professionals) | 3 | 30% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Spain | 1 | <1% |
United States | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 105 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 24% |
Student > Bachelor | 16 | 15% |
Researcher | 12 | 11% |
Student > Doctoral Student | 9 | 8% |
Student > Master | 9 | 8% |
Other | 20 | 18% |
Unknown | 18 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 25 | 23% |
Medicine and Dentistry | 24 | 22% |
Biochemistry, Genetics and Molecular Biology | 11 | 10% |
Sports and Recreations | 9 | 8% |
Nursing and Health Professions | 4 | 4% |
Other | 14 | 13% |
Unknown | 23 | 21% |