| Title |
CRISPR Interference Directs Strand Specific Spacer Acquisition
|
|---|---|
| Published in |
PLOS ONE, April 2012
|
| DOI | 10.1371/journal.pone.0035888 |
| Pubmed ID | |
| Authors |
Daan C. Swarts, Cas Mosterd, Mark W. J. van Passel, Stan J. J. Brouns |
| Abstract |
CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders. In Escherichia coli, transcripts of these loci are cleaved into small RNAs and utilized by the Cascade complex to bind invader DNA, which is then likely degraded by Cas3 during CRISPR interference. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 533 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| Spain | 2 | <1% |
| India | 2 | <1% |
| Chile | 1 | <1% |
| Netherlands | 1 | <1% |
| Germany | 1 | <1% |
| Denmark | 1 | <1% |
| Switzerland | 1 | <1% |
| Japan | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 519 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 125 | 23% |
| Student > Bachelor | 100 | 19% |
| Student > Master | 95 | 18% |
| Researcher | 55 | 10% |
| Student > Doctoral Student | 18 | 3% |
| Other | 51 | 10% |
| Unknown | 89 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 205 | 38% |
| Biochemistry, Genetics and Molecular Biology | 170 | 32% |
| Immunology and Microbiology | 23 | 4% |
| Medicine and Dentistry | 9 | 2% |
| Engineering | 7 | 1% |
| Other | 30 | 6% |
| Unknown | 89 | 17% |