Title |
Collection of Aerosolized Human Cytokines Using Teflon® Filters
|
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Published in |
PLOS ONE, May 2012
|
DOI | 10.1371/journal.pone.0035814 |
Pubmed ID | |
Authors |
Jennifer H. McKenzie, James J. McDevitt, M. Patricia Fabian, Grace M. Hwang, Donald K. Milton |
Abstract |
Collection of exhaled breath samples for the analysis of inflammatory biomarkers is an important area of research aimed at improving our ability to diagnose, treat and understand the mechanisms of chronic pulmonary disease. Current collection methods based on condensation of water vapor from exhaled breath yield biomarker levels at or near the detection limits of immunoassays contributing to problems with reproducibility and validity of biomarker measurements. In this study, we compare the collection efficiency of two aerosol-to-liquid sampling devices to a filter-based collection method for recovery of dilute laboratory generated aerosols of human cytokines so as to identify potential alternatives to exhaled breath condensate collection. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 6% |
Unknown | 16 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 29% |
Student > Ph. D. Student | 4 | 24% |
Other | 2 | 12% |
Professor | 2 | 12% |
Professor > Associate Professor | 2 | 12% |
Other | 1 | 6% |
Unknown | 1 | 6% |
Readers by discipline | Count | As % |
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Environmental Science | 4 | 24% |
Chemistry | 3 | 18% |
Medicine and Dentistry | 3 | 18% |
Computer Science | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Other | 2 | 12% |
Unknown | 3 | 18% |