Title |
Comparative Analysis of the Heptahelical Transmembrane Bundles of G Protein-Coupled Receptors
|
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Published in |
PLOS ONE, April 2012
|
DOI | 10.1371/journal.pone.0035802 |
Pubmed ID | |
Authors |
Tetsuji Okada |
Abstract |
G protein-coupled receptors represent a large family of eukaryotic membrane proteins, and are involved in almost all physiological processes in humans. Recent advances in the crystallographic study of these receptors enable a detailed comparative analysis of the commonly shared heptahelical transmembrane bundle. Systematic comparison of the bundles from a variety of receptors is indispensable for understanding not only of the structural diversification optimized for the binding of respective ligands but also of the structural conservation required for the common mechanism of activation accompanying the interaction changes among the seven helices. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 25% |
Student > Master | 4 | 17% |
Student > Bachelor | 2 | 8% |
Lecturer | 2 | 8% |
Researcher | 2 | 8% |
Other | 4 | 17% |
Unknown | 4 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 38% |
Chemistry | 5 | 21% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Computer Science | 1 | 4% |
Other | 3 | 13% |
Unknown | 4 | 17% |