Title |
Ghrelin Treatment of Cachectic Patients with Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
|
---|---|
Published in |
PLOS ONE, May 2012
|
DOI | 10.1371/journal.pone.0035708 |
Pubmed ID | |
Authors |
Keisuke Miki, Ryoji Maekura, Noritoshi Nagaya, Masamitsu Nakazato, Hiroshi Kimura, Shinsuke Murakami, Shunsuke Ohnishi, Toru Hiraga, Mari Miki, Seigo Kitada, Kenji Yoshimura, Yoshitaka Tateishi, Yasuji Arimura, Nobuhiro Matsumoto, Masanori Yoshikawa, Kenichi Yamahara, Kenji Kangawa |
Abstract |
Pulmonary cachexia is common in advanced chronic obstructive pulmonary disease (COPD), culminating in exercise intolerance and a poor prognosis. Ghrelin is a novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy and safety of adding ghrelin to pulmonary rehabilitation (PR) in cachectic COPD patients were investigated. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 162 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
United Kingdom | 2 | 1% |
Brazil | 1 | <1% |
Japan | 1 | <1% |
Spain | 1 | <1% |
Unknown | 155 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 34 | 21% |
Student > Ph. D. Student | 20 | 12% |
Student > Bachelor | 14 | 9% |
Researcher | 13 | 8% |
Student > Doctoral Student | 10 | 6% |
Other | 32 | 20% |
Unknown | 39 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 48 | 30% |
Nursing and Health Professions | 26 | 16% |
Sports and Recreations | 12 | 7% |
Psychology | 9 | 6% |
Biochemistry, Genetics and Molecular Biology | 7 | 4% |
Other | 18 | 11% |
Unknown | 42 | 26% |