Report for: Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study

Title	Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study
Published in	PLOS ONE, April 2012
DOI	10.1371/journal.pone.0035425
Pubmed ID	22545106
Authors	Inger Vedin, Tommy Cederholm, Yvonne Freund-Levi, Hans Basun, Anita Garlind, Gerd Faxén Irving, Maria Eriksdotter-Jönhagen, Lars-Olof Wahlund, Ingrid Dahlman, Jan Palmblad
Abstract	Dietary fish oil, rich in n-3 fatty acids (n-3 FAs), e.g. docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), regulate inflammatory reactions by various mechanisms, e.g. gene activation. However, the effects of long-term treatment with DHA and EPA in humans, using genome wide techniques, are poorly described. Hence, our aim was to determine the effects of 6 mo of dietary supplementation with an n-3 FA preparation rich in DHA on global gene expression in peripheral blood mononuclear cells.

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Readers by professional status	Count	As %
Student > Master	21	17%
Student > Bachelor	18	15%
Researcher	15	12%
Student > Ph. D. Student	13	11%
Other	8	7%
Other	18	15%
Unknown	30	24%

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Agricultural and Biological Sciences	26	21%
Medicine and Dentistry	20	16%
Biochemistry, Genetics and Molecular Biology	14	11%
Nursing and Health Professions	7	6%
Neuroscience	6	5%
Other	12	10%
Unknown	38	31%

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