| Title |
Endothelial and Smooth Muscle Cells from Abdominal Aortic Aneurysm Have Increased Oxidative Stress and Telomere Attrition
|
|---|---|
| Published in |
PLOS ONE, April 2012
|
| DOI | 10.1371/journal.pone.0035312 |
| Pubmed ID | |
| Authors |
Giuseppe Cafueri, Federica Parodi, Angela Pistorio, Maria Bertolotto, Francesco Ventura, Claudio Gambini, Paolo Bianco, Franco Dallegri, Vito Pistoia, Annalisa Pezzolo, Domenico Palombo |
| Abstract |
Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease with life-threatening complications. AAA is typically asymptomatic and its rupture is associated with high mortality rate. Both environmental and genetic risk factors are involved in AAA pathogenesis. Aim of this study was to investigate telomere length (TL) and oxidative DNA damage in paired blood lymphocytes, aortic endothelial cells (EC), vascular smooth muscle cells (VSMC), and epidermal cells from patients with AAA in comparison with matched controls. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| Unknown | 54 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 18% |
| Student > Bachelor | 10 | 18% |
| Student > Master | 7 | 13% |
| Professor | 4 | 7% |
| Researcher | 4 | 7% |
| Other | 14 | 25% |
| Unknown | 7 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 32% |
| Agricultural and Biological Sciences | 10 | 18% |
| Biochemistry, Genetics and Molecular Biology | 9 | 16% |
| Engineering | 3 | 5% |
| Unspecified | 2 | 4% |
| Other | 7 | 13% |
| Unknown | 7 | 13% |