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A Single Nucleotide Polymorphism within the Novel Sex-Linked Testis-Specific Retrotransposed PGAM4 Gene Influences Human Male Fertility

Overview of attention for article published in PLOS ONE, May 2012
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Title
A Single Nucleotide Polymorphism within the Novel Sex-Linked Testis-Specific Retrotransposed PGAM4 Gene Influences Human Male Fertility
Published in
PLOS ONE, May 2012
DOI 10.1371/journal.pone.0035195
Pubmed ID
Authors

Hidenobu Okuda, Akira Tsujimura, Shinji Irie, Keisuke Yamamoto, Shinichiro Fukuhara, Yasuhiro Matsuoka, Tetsuya Takao, Yasushi Miyagawa, Norio Nonomura, Morimasa Wada, Hiromitsu Tanaka

Abstract

The development of novel fertilization treatments, including in vitro fertilization and intracytoplasmic injection, has made pregnancy possible regardless of the level of activity of the spermatozoa; however, the etiology of male-factor infertility is poorly understood. Multiple studies, primarily through the use of transgenic animals, have contributed to a list of candidate genes that may affect male infertility in humans. We examined single nucleotide polymorphisms (SNPs) as a cause of male infertility in an analysis of spermatogenesis-specific genes.

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Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 22%
Researcher 4 15%
Professor 3 11%
Professor > Associate Professor 2 7%
Student > Bachelor 2 7%
Other 3 11%
Unknown 7 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 30%
Medicine and Dentistry 5 19%
Computer Science 3 11%
Biochemistry, Genetics and Molecular Biology 2 7%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 7 26%