Title |
A Single Nucleotide Polymorphism within the Novel Sex-Linked Testis-Specific Retrotransposed PGAM4 Gene Influences Human Male Fertility
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Published in |
PLOS ONE, May 2012
|
DOI | 10.1371/journal.pone.0035195 |
Pubmed ID | |
Authors |
Hidenobu Okuda, Akira Tsujimura, Shinji Irie, Keisuke Yamamoto, Shinichiro Fukuhara, Yasuhiro Matsuoka, Tetsuya Takao, Yasushi Miyagawa, Norio Nonomura, Morimasa Wada, Hiromitsu Tanaka |
Abstract |
The development of novel fertilization treatments, including in vitro fertilization and intracytoplasmic injection, has made pregnancy possible regardless of the level of activity of the spermatozoa; however, the etiology of male-factor infertility is poorly understood. Multiple studies, primarily through the use of transgenic animals, have contributed to a list of candidate genes that may affect male infertility in humans. We examined single nucleotide polymorphisms (SNPs) as a cause of male infertility in an analysis of spermatogenesis-specific genes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 22% |
Researcher | 4 | 15% |
Professor | 3 | 11% |
Professor > Associate Professor | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 3 | 11% |
Unknown | 7 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 30% |
Medicine and Dentistry | 5 | 19% |
Computer Science | 3 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Immunology and Microbiology | 1 | 4% |
Other | 1 | 4% |
Unknown | 7 | 26% |