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Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria

Overview of attention for article published in PLOS ONE, April 2012
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Title
Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria
Published in
PLOS ONE, April 2012
DOI 10.1371/journal.pone.0034676
Pubmed ID
Authors

Josep Bassaganya-Riera, Monica Viladomiu, Mireia Pedragosa, Claudio De Simone, Raquel Hontecillas

Abstract

Inflammatory bowel disease (IBD) increases the risk of colorectal cancer. Probiotic bacteria produce immunoregulatory metabolites in vitro such as conjugated linoleic acid (CLA), a polyunsaturated fatty acid with potent anti-carcinogenic effects. This study aimed to investigate the cellular and molecular mechanisms underlying the efficacy of probiotic bacteria in mouse models of cancer.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 <1%
Italy 1 <1%
Brazil 1 <1%
Unknown 139 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 31 22%
Student > Bachelor 22 15%
Student > Ph. D. Student 19 13%
Researcher 16 11%
Professor 6 4%
Other 25 18%
Unknown 23 16%
Readers by discipline Count As %
Medicine and Dentistry 36 25%
Agricultural and Biological Sciences 26 18%
Biochemistry, Genetics and Molecular Biology 18 13%
Immunology and Microbiology 13 9%
Nursing and Health Professions 8 6%
Other 11 8%
Unknown 30 21%