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Placental 11-Beta Hydroxysteroid Dehydrogenase Methylation Is Associated with Newborn Growth and a Measure of Neurobehavioral Outcome

Overview of attention for article published in PLOS ONE, March 2012
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Title
Placental 11-Beta Hydroxysteroid Dehydrogenase Methylation Is Associated with Newborn Growth and a Measure of Neurobehavioral Outcome
Published in
PLOS ONE, March 2012
DOI 10.1371/journal.pone.0033794
Pubmed ID
Authors

Carmen J. Marsit, Matthew A. Maccani, James F. Padbury, Barry M. Lester

Abstract

There is growing evidence that the intrauterine environment can impact the neurodevelopment of the fetus through alterations in the functional epigenome of the placenta. In the placenta, the HSD11B2 gene encoding the 11-beta hydroxysteroid dehydrogenase enzyme, which is responsible for the inactivation of maternal cortisol, is regulated by DNA methylation, and has been shown to be susceptible to stressors from the maternal environment.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 <1%
Ireland 1 <1%
Unknown 159 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 43 27%
Researcher 22 14%
Student > Doctoral Student 17 11%
Student > Bachelor 16 10%
Student > Master 16 10%
Other 22 14%
Unknown 25 16%
Readers by discipline Count As %
Medicine and Dentistry 35 22%
Agricultural and Biological Sciences 23 14%
Psychology 22 14%
Nursing and Health Professions 8 5%
Biochemistry, Genetics and Molecular Biology 8 5%
Other 26 16%
Unknown 39 24%