Title |
Placental 11-Beta Hydroxysteroid Dehydrogenase Methylation Is Associated with Newborn Growth and a Measure of Neurobehavioral Outcome
|
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Published in |
PLOS ONE, March 2012
|
DOI | 10.1371/journal.pone.0033794 |
Pubmed ID | |
Authors |
Carmen J. Marsit, Matthew A. Maccani, James F. Padbury, Barry M. Lester |
Abstract |
There is growing evidence that the intrauterine environment can impact the neurodevelopment of the fetus through alterations in the functional epigenome of the placenta. In the placenta, the HSD11B2 gene encoding the 11-beta hydroxysteroid dehydrogenase enzyme, which is responsible for the inactivation of maternal cortisol, is regulated by DNA methylation, and has been shown to be susceptible to stressors from the maternal environment. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | <1% |
Ireland | 1 | <1% |
Unknown | 159 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 43 | 27% |
Researcher | 22 | 14% |
Student > Doctoral Student | 17 | 11% |
Student > Bachelor | 16 | 10% |
Student > Master | 16 | 10% |
Other | 22 | 14% |
Unknown | 25 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 35 | 22% |
Agricultural and Biological Sciences | 23 | 14% |
Psychology | 22 | 14% |
Nursing and Health Professions | 8 | 5% |
Biochemistry, Genetics and Molecular Biology | 8 | 5% |
Other | 26 | 16% |
Unknown | 39 | 24% |