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Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era

Overview of attention for article published in PLOS ONE, March 2012
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Title
Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era
Published in
PLOS ONE, March 2012
DOI 10.1371/journal.pone.0033684
Pubmed ID
Authors

Christine Carico, Miriam Nuño, Debraj Mukherjee, Adam Elramsisy, Jocelynn Dantis, Jethro Hu, Jeremy Rudnick, John S. Yu, Keith L. Black, Serguei I. Bannykh, Chirag G. Patil

Abstract

Pre-temozolomide studies demonstrated that loss of the tumor suppressor gene PTEN held independent prognostic significance in GBM patients. We investigated whether loss of PTEN predicted shorter survival in the temozolomide era. The role of PTEN in the PI3K/Akt pathway is also reviewed.

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Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
India 1 1%
United States 1 1%
Brazil 1 1%
Unknown 84 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 19%
Student > Master 13 15%
Student > Bachelor 9 10%
Researcher 9 10%
Student > Postgraduate 8 9%
Other 17 19%
Unknown 15 17%
Readers by discipline Count As %
Medicine and Dentistry 31 35%
Biochemistry, Genetics and Molecular Biology 20 23%
Agricultural and Biological Sciences 9 10%
Neuroscience 8 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 4 5%
Unknown 15 17%