Title |
Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era
|
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Published in |
PLOS ONE, March 2012
|
DOI | 10.1371/journal.pone.0033684 |
Pubmed ID | |
Authors |
Christine Carico, Miriam Nuño, Debraj Mukherjee, Adam Elramsisy, Jocelynn Dantis, Jethro Hu, Jeremy Rudnick, John S. Yu, Keith L. Black, Serguei I. Bannykh, Chirag G. Patil |
Abstract |
Pre-temozolomide studies demonstrated that loss of the tumor suppressor gene PTEN held independent prognostic significance in GBM patients. We investigated whether loss of PTEN predicted shorter survival in the temozolomide era. The role of PTEN in the PI3K/Akt pathway is also reviewed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 1% |
India | 1 | 1% |
United States | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 84 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 19% |
Student > Master | 13 | 15% |
Student > Bachelor | 9 | 10% |
Researcher | 9 | 10% |
Student > Postgraduate | 8 | 9% |
Other | 17 | 19% |
Unknown | 15 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 31 | 35% |
Biochemistry, Genetics and Molecular Biology | 20 | 23% |
Agricultural and Biological Sciences | 9 | 10% |
Neuroscience | 8 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
Other | 4 | 5% |
Unknown | 15 | 17% |