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Increased Expression and Altered Methylation of HERVWE1 in the Human Placentas of Smaller Fetuses from Monozygotic, Dichorionic, Discordant Twins

Overview of attention for article published in PLOS ONE, March 2012
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Title
Increased Expression and Altered Methylation of HERVWE1 in the Human Placentas of Smaller Fetuses from Monozygotic, Dichorionic, Discordant Twins
Published in
PLOS ONE, March 2012
DOI 10.1371/journal.pone.0033503
Pubmed ID
Authors

Yu Gao, Zhiming He, Zilian Wang, Yanmin Luo, Hongyu Sun, Yi Zhou, Linhuan Huang, Manchao Li, Qun Fang, Shiwen Jiang

Abstract

The human endogenous retroviral family W, Env(C7), member 1 gene (HERVWE1) is thought to participate in trophoblast cell fusion, and its expression is diminished in the placentas of singleton intrauterine growth-retarded pregnancies. However, there is limited information about the role of HERVWE1 in discordant fetal growth in twins. This study was to compare HERVWE1 gene expression between the placentas of discordant monozygotic twins and to identify its regulation by methylation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Researcher 5 16%
Student > Bachelor 3 9%
Student > Master 3 9%
Professor 3 9%
Other 6 19%
Unknown 6 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 16%
Medicine and Dentistry 5 16%
Agricultural and Biological Sciences 5 16%
Veterinary Science and Veterinary Medicine 2 6%
Nursing and Health Professions 1 3%
Other 5 16%
Unknown 9 28%