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Genome-Wide DNA Methylation Indicates Silencing of Tumor Suppressor Genes in Uterine Leiomyoma

Overview of attention for article published in PLOS ONE, March 2012
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Title
Genome-Wide DNA Methylation Indicates Silencing of Tumor Suppressor Genes in Uterine Leiomyoma
Published in
PLOS ONE, March 2012
DOI 10.1371/journal.pone.0033284
Pubmed ID
Authors

Antonia Navarro, Ping Yin, Diana Monsivais, Simon M. Lin, Pan Du, Jian-Jun Wei, Serdar E. Bulun

Abstract

Uterine leiomyomas, or fibroids, represent the most common benign tumor of the female reproductive tract. Fibroids become symptomatic in 30% of all women and up to 70% of African American women of reproductive age. Epigenetic dysregulation of individual genes has been demonstrated in leiomyoma cells; however, the in vivo genome-wide distribution of such epigenetic abnormalities remains unknown.

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Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Germany 1 2%
Unknown 58 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 25%
Student > Ph. D. Student 7 11%
Student > Master 6 10%
Student > Doctoral Student 4 7%
Student > Postgraduate 4 7%
Other 10 16%
Unknown 15 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 21%
Biochemistry, Genetics and Molecular Biology 11 18%
Medicine and Dentistry 9 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Nursing and Health Professions 1 2%
Other 8 13%
Unknown 17 28%