Title |
Genome-Wide DNA Methylation Indicates Silencing of Tumor Suppressor Genes in Uterine Leiomyoma
|
---|---|
Published in |
PLOS ONE, March 2012
|
DOI | 10.1371/journal.pone.0033284 |
Pubmed ID | |
Authors |
Antonia Navarro, Ping Yin, Diana Monsivais, Simon M. Lin, Pan Du, Jian-Jun Wei, Serdar E. Bulun |
Abstract |
Uterine leiomyomas, or fibroids, represent the most common benign tumor of the female reproductive tract. Fibroids become symptomatic in 30% of all women and up to 70% of African American women of reproductive age. Epigenetic dysregulation of individual genes has been demonstrated in leiomyoma cells; however, the in vivo genome-wide distribution of such epigenetic abnormalities remains unknown. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
United States | 1 | 2% |
Germany | 1 | 2% |
Unknown | 58 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 25% |
Student > Ph. D. Student | 7 | 11% |
Student > Master | 6 | 10% |
Student > Doctoral Student | 4 | 7% |
Student > Postgraduate | 4 | 7% |
Other | 10 | 16% |
Unknown | 15 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 21% |
Biochemistry, Genetics and Molecular Biology | 11 | 18% |
Medicine and Dentistry | 9 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Nursing and Health Professions | 1 | 2% |
Other | 8 | 13% |
Unknown | 17 | 28% |