| Title |
Detection of IL28B SNP DNA from Buccal Epithelial Cells, Small Amounts of Serum, and Dried Blood Spots
|
|---|---|
| Published in |
PLOS ONE, March 2012
|
| DOI | 10.1371/journal.pone.0033000 |
| Pubmed ID | |
| Authors |
Philippe Halfon, Denis Ouzan, Hacène Khiri, Guillaume Pénaranda, Paul Castellani, Valerie Oulès, Asma Kahloun, Nolwenn Amrani, Lise Fanteria, Agnès Martineau, Lou Naldi, Marc Bourlière |
| Abstract |
Point mutations in the coding region of the interleukin 28 gene (rs12979860) have recently been identified for predicting the outcome of treatment of hepatitis C virus infection. This polymorphism detection was based on whole blood DNA extraction. Alternatively, DNA for genetic diagnosis has been derived from buccal epithelial cells (BEC), dried blood spots (DBS), and genomic DNA from serum. The aim of the study was to investigate the reliability and accuracy of alternative routes of testing for single nucleotide polymorphism allele rs12979860CC. |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 24% |
| Researcher | 6 | 18% |
| Other | 4 | 12% |
| Student > Bachelor | 3 | 9% |
| Student > Postgraduate | 3 | 9% |
| Other | 5 | 15% |
| Unknown | 5 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 38% |
| Medicine and Dentistry | 6 | 18% |
| Biochemistry, Genetics and Molecular Biology | 4 | 12% |
| Immunology and Microbiology | 2 | 6% |
| Physics and Astronomy | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 7 | 21% |