| Title |
Circadian Gene Variants and Susceptibility to Type 2 Diabetes: A Pilot Study
|
|---|---|
| Published in |
PLOS ONE, April 2012
|
| DOI | 10.1371/journal.pone.0032670 |
| Pubmed ID | |
| Authors |
M. Ann Kelly, Simon D. Rees, M. Zafar I. Hydrie, A. Samad Shera, Srikanth Bellary, J. Paul O’Hare, Sudhesh Kumar, Shahrad Taheri, Abdul Basit, Anthony H. Barnett |
| Abstract |
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility. We present the results of a pilot study investigating the association between type 2 diabetes and selected single nucleotide polymorphisms (SNPs) in/near nine circadian genes. The variants were chosen based on their previously reported association with prostate cancer, a disease that has been suggested to have a genetic link with type 2 diabetes through a number of shared inherited risk determinants. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Germany | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 1% |
| India | 1 | 1% |
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| Croatia | 1 | 1% |
| Unknown | 93 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 22% |
| Researcher | 17 | 17% |
| Student > Master | 12 | 12% |
| Student > Bachelor | 6 | 6% |
| Lecturer > Senior Lecturer | 4 | 4% |
| Other | 19 | 19% |
| Unknown | 18 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 24% |
| Agricultural and Biological Sciences | 22 | 22% |
| Biochemistry, Genetics and Molecular Biology | 14 | 14% |
| Nursing and Health Professions | 5 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Other | 9 | 9% |
| Unknown | 20 | 20% |