| Title |
Nicotine-Like Effects of the Neonicotinoid Insecticides Acetamiprid and Imidacloprid on Cerebellar Neurons from Neonatal Rats
|
|---|---|
| Published in |
PLOS ONE, February 2012
|
| DOI | 10.1371/journal.pone.0032432 |
| Pubmed ID | |
| Authors |
Junko Kimura-Kuroda, Yukari Komuta, Yoichiro Kuroda, Masaharu Hayashi, Hitoshi Kawano |
| Abstract |
Acetamiprid (ACE) and imidacloprid (IMI) belong to a new, widely used class of pesticide, the neonicotinoids. With similar chemical structures to nicotine, neonicotinoids also share agonist activity at nicotinic acetylcholine receptors (nAChRs). Although their toxicities against insects are well established, their precise effects on mammalian nAChRs remain to be elucidated. Because of the importance of nAChRs for mammalian brain function, especially brain development, detailed investigation of the neonicotinoids is needed to protect the health of human children. We aimed to determine the effects of neonicotinoids on the nAChRs of developing mammalian neurons and compare their effects with nicotine, a neurotoxin of brain development. |
X Demographics
The data shown below were collected from the profiles of 77 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 10 | 13% |
| Japan | 8 | 10% |
| United States | 5 | 6% |
| Malaysia | 4 | 5% |
| United Kingdom | 4 | 5% |
| Turkey | 2 | 3% |
| Philippines | 2 | 3% |
| Côte d'Ivoire | 1 | 1% |
| Chile | 1 | 1% |
| Other | 7 | 9% |
| Unknown | 33 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 71 | 92% |
| Scientists | 5 | 6% |
| Practitioners (doctors, other healthcare professionals) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 270 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Norway | 1 | <1% |
| Canada | 1 | <1% |
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Taiwan | 1 | <1% |
| Unknown | 261 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 49 | 18% |
| Student > Master | 45 | 17% |
| Researcher | 37 | 14% |
| Student > Ph. D. Student | 27 | 10% |
| Student > Doctoral Student | 12 | 4% |
| Other | 52 | 19% |
| Unknown | 48 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 29% |
| Environmental Science | 30 | 11% |
| Biochemistry, Genetics and Molecular Biology | 23 | 9% |
| Medicine and Dentistry | 18 | 7% |
| Chemistry | 11 | 4% |
| Other | 48 | 18% |
| Unknown | 62 | 23% |