Title |
Phylo: A Citizen Science Approach for Improving Multiple Sequence Alignment
|
---|---|
Published in |
PLOS ONE, March 2012
|
DOI | 10.1371/journal.pone.0031362 |
Pubmed ID | |
Authors |
Alexander Kawrykow, Gary Roumanis, Alfred Kam, Daniel Kwak, Clarence Leung, Chu Wu, Eleyine Zarour, Luis Sarmenta, Mathieu Blanchette, Jérôme Waldispühl |
Abstract |
Comparative genomics, or the study of the relationships of genome structure and function across different species, offers a powerful tool for studying evolution, annotating genomes, and understanding the causes of various genetic disorders. However, aligning multiple sequences of DNA, an essential intermediate step for most types of analyses, is a difficult computational task. In parallel, citizen science, an approach that takes advantage of the fact that the human brain is exquisitely tuned to solving specific types of problems, is becoming increasingly popular. There, instances of hard computational problems are dispatched to a crowd of non-expert human game players and solutions are sent back to a central server. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 10 | 26% |
Canada | 4 | 10% |
United Kingdom | 2 | 5% |
Germany | 2 | 5% |
Bosnia and Herzegovina | 1 | 3% |
Egypt | 1 | 3% |
Australia | 1 | 3% |
France | 1 | 3% |
Cameroon | 1 | 3% |
Other | 0 | 0% |
Unknown | 16 | 41% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 19 | 49% |
Members of the public | 19 | 49% |
Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 17 | 6% |
Germany | 5 | 2% |
United Kingdom | 4 | 1% |
France | 3 | 1% |
Canada | 3 | 1% |
Brazil | 2 | <1% |
Spain | 2 | <1% |
Switzerland | 2 | <1% |
Finland | 1 | <1% |
Other | 6 | 2% |
Unknown | 247 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 66 | 23% |
Student > Ph. D. Student | 65 | 22% |
Student > Master | 37 | 13% |
Student > Bachelor | 23 | 8% |
Other | 20 | 7% |
Other | 44 | 15% |
Unknown | 37 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 88 | 30% |
Computer Science | 53 | 18% |
Social Sciences | 19 | 7% |
Environmental Science | 14 | 5% |
Biochemistry, Genetics and Molecular Biology | 12 | 4% |
Other | 62 | 21% |
Unknown | 44 | 15% |