| Title |
A Double-Blind, Placebo-Controlled, Randomized, Clinical Trial of the TLR-3 Agonist Rintatolimod in Severe Cases of Chronic Fatigue Syndrome
|
|---|---|
| Published in |
PLOS ONE, March 2012
|
| DOI | 10.1371/journal.pone.0031334 |
| Pubmed ID | |
| Authors |
David R. Strayer, William A. Carter, Bruce C. Stouch, Staci R. Stevens, Lucinda Bateman, Paul J. Cimoch, Charles W. Lapp, Daniel L. Peterson, William M. Mitchell |
| Abstract |
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a severely debilitating disease of unknown pathogenesis consisting of a variety of symptoms including severe fatigue. The objective of the study was to examine the efficacy and safety of a TLR-3 agonist, rintatolimod (Poly I: C(12)U), in patients with debilitating CFS/ME. |
X Demographics
The data shown below were collected from the profiles of 36 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 19% |
| Netherlands | 4 | 11% |
| United Kingdom | 3 | 8% |
| Canada | 2 | 6% |
| France | 1 | 3% |
| Norway | 1 | 3% |
| Unknown | 18 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 81% |
| Science communicators (journalists, bloggers, editors) | 3 | 8% |
| Practitioners (doctors, other healthcare professionals) | 2 | 6% |
| Scientists | 2 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Sweden | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 123 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 17% |
| Student > Master | 17 | 13% |
| Student > Bachelor | 16 | 13% |
| Other | 12 | 9% |
| Student > Doctoral Student | 9 | 7% |
| Other | 21 | 17% |
| Unknown | 30 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 28% |
| Agricultural and Biological Sciences | 18 | 14% |
| Immunology and Microbiology | 7 | 6% |
| Nursing and Health Professions | 6 | 5% |
| Biochemistry, Genetics and Molecular Biology | 6 | 5% |
| Other | 24 | 19% |
| Unknown | 30 | 24% |