Title |
Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity
|
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Published in |
PLOS ONE, January 2012
|
DOI | 10.1371/journal.pone.0030898 |
Pubmed ID | |
Authors |
Natalija Budimir, Anke Huckriede, Tjarko Meijerhof, Louis Boon, Emma Gostick, David A. Price, Jan Wilschut, Aalzen de Haan |
Abstract |
The inability of seasonal influenza vaccines to effectively protect against infection with antigenically drifted viruses or newly emerging pandemic viruses underlines the need for development of cross-reactive influenza vaccines that induce immunity against a variety of virus subtypes. Therefore, potential cross-protective vaccines, e.g., whole inactivated virus (WIV) vaccine, that can target conserved internal antigens such as the nucleoprotein (NP) and/or matrix protein (M1) need to be explored. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 59 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 31% |
Researcher | 14 | 24% |
Student > Master | 12 | 20% |
Student > Doctoral Student | 2 | 3% |
Student > Bachelor | 2 | 3% |
Other | 3 | 5% |
Unknown | 8 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 29% |
Medicine and Dentistry | 12 | 20% |
Immunology and Microbiology | 9 | 15% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Nursing and Health Professions | 1 | 2% |
Other | 8 | 14% |
Unknown | 8 | 14% |