| Title |
Efficient Induction of Extrinsic Cell Death by Dandelion Root Extract in Human Chronic Myelomonocytic Leukemia (CMML) Cells
|
|---|---|
| Published in |
PLOS ONE, February 2012
|
| DOI | 10.1371/journal.pone.0030604 |
| Pubmed ID | |
| Authors |
Pamela Ovadje, Caroline Hamm, Siyaram Pandey |
| Abstract |
Chronic Myelomonocytic Leukemia (CMML) is a heterogeneous disease that is not only hard to diagnose and classify, but is also highly resistant to treatment. Available forms of therapy for this disease have not shown significant effects and patients rapidly develop resistance early on in therapy. These factors lead to the very poor prognosis observed with CMML patients, with median survival duration between 12 and 24 months after diagnosis. This study is therefore centered around evaluating the selective efficacy of a natural extract from dandelion roots, in inducing programmed cell death in aggressive and resistant CMML cell lines. |
X Demographics
The data shown below were collected from the profiles of 55 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 18 | 33% |
| Canada | 5 | 9% |
| United Kingdom | 3 | 5% |
| Australia | 2 | 4% |
| Spain | 1 | 2% |
| Bahamas | 1 | 2% |
| Pakistan | 1 | 2% |
| Mexico | 1 | 2% |
| Unknown | 23 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 51 | 93% |
| Practitioners (doctors, other healthcare professionals) | 2 | 4% |
| Scientists | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 1% |
| United States | 1 | 1% |
| Ghana | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 65 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 22% |
| Other | 8 | 12% |
| Student > Doctoral Student | 8 | 12% |
| Student > Master | 7 | 10% |
| Researcher | 7 | 10% |
| Other | 13 | 19% |
| Unknown | 11 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 25% |
| Agricultural and Biological Sciences | 10 | 14% |
| Biochemistry, Genetics and Molecular Biology | 7 | 10% |
| Chemistry | 4 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Other | 15 | 22% |
| Unknown | 13 | 19% |