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Single-Cell Analysis of Murine Long-Term Hematopoietic Stem Cells Reveals Distinct Patterns of Gene Expression during Fetal Migration

Overview of attention for article published in PLOS ONE, January 2012
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Title
Single-Cell Analysis of Murine Long-Term Hematopoietic Stem Cells Reveals Distinct Patterns of Gene Expression during Fetal Migration
Published in
PLOS ONE, January 2012
DOI 10.1371/journal.pone.0030542
Pubmed ID
Authors

Jesús Ciriza, Dominique Hall, Alison Lu, Joseph Robert De Sena, Mufadhal Al-Kuhlani, Marcos E. García-Ojeda

Abstract

Long-term hematopoietic stem cells (LT-HSCs) migrate from the fetal liver (FL) to the fetal bone marrow (FBM) during development. Various adhesion and chemotactic receptor genes have been implicated in the migration of adult LT-HSCs. However, their role in the migration of fetal LT-HSCs is not clearly understood due, in part, to the rare number of these cells in fetal tissues, which preclude classical gene expression analysis. The aim of this study is to characterize the expression of migration related genes in fetal LT-HSC across different anatomical locations during development.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 31%
Researcher 13 24%
Student > Bachelor 6 11%
Student > Master 6 11%
Professor 4 7%
Other 5 9%
Unknown 3 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 35%
Biochemistry, Genetics and Molecular Biology 9 17%
Medicine and Dentistry 8 15%
Immunology and Microbiology 3 6%
Engineering 2 4%
Other 7 13%
Unknown 6 11%