| Title |
Ex Vivo Expansion of Human CD8+ T Cells Using Autologous CD4+ T Cell Help
|
|---|---|
| Published in |
PLOS ONE, January 2012
|
| DOI | 10.1371/journal.pone.0030229 |
| Pubmed ID | |
| Authors |
Marcus O. Butler, Osamu Imataki, Yoshihiro Yamashita, Makito Tanaka, Sascha Ansén, Alla Berezovskaya, Genita Metzler, Matthew I. Milstein, Mary M. Mooney, Andrew P. Murray, Hiroyuki Mano, Lee M. Nadler, Naoto Hirano |
| Abstract |
Using in vivo mouse models, the mechanisms of CD4+ T cell help have been intensively investigated. However, a mechanistic analysis of human CD4+ T cell help is largely lacking. Our goal was to elucidate the mechanisms of human CD4+ T cell help of CD8+ T cell proliferation using a novel in vitro model. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Australia | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Germany | 2 | 2% |
| Portugal | 1 | <1% |
| Unknown | 98 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 21% |
| Student > Ph. D. Student | 19 | 18% |
| Student > Bachelor | 15 | 14% |
| Student > Master | 9 | 9% |
| Student > Doctoral Student | 6 | 6% |
| Other | 16 | 15% |
| Unknown | 17 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 19% |
| Medicine and Dentistry | 17 | 16% |
| Biochemistry, Genetics and Molecular Biology | 15 | 14% |
| Immunology and Microbiology | 12 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Other | 14 | 13% |
| Unknown | 20 | 19% |