| Title |
Efficacy of Infection Control Interventions in Reducing the Spread of Multidrug-Resistant Organisms in the Hospital Setting
|
|---|---|
| Published in |
PLOS ONE, February 2012
|
| DOI | 10.1371/journal.pone.0030170 |
| Pubmed ID | |
| Authors |
Erika M. C. D'Agata, Mary Ann Horn, Shigui Ruan, Glenn F. Webb, Joanna R. Wares |
| Abstract |
Multidrug-resistant organisms (MDRO) continue to spread in hospitals globally, but the population-level impact of recommended preventive strategies and the relative benefit of individual strategies targeting all MDRO in the hospital setting are unclear. To explore the dynamics of MDRO transmission in the hospital, we develop a model extending data from clinical individual-level studies to quantify the impact of hand hygiene, contact precautions, reducing antimicrobial exposure and screening surveillance cultures in decreasing the prevalence of MDRO colonization and infection. The effect of an ongoing increase in the influx of patients colonized with MDRO into the hospital setting is also quantified. We find that most recommended strategies have substantial effect in decreasing the prevalence of MDRO over time. However, screening for asymptomatic MDRO colonization among patients who are not receiving antimicrobials is of minimal value in reducing the spread of MDRO. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 17% |
| Netherlands | 1 | 17% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 3 | 50% |
| Members of the public | 2 | 33% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 2 | 2% |
| France | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Taiwan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 95 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 17% |
| Student > Bachelor | 13 | 13% |
| Researcher | 10 | 10% |
| Student > Ph. D. Student | 10 | 10% |
| Student > Postgraduate | 9 | 9% |
| Other | 19 | 19% |
| Unknown | 23 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 40 | 40% |
| Nursing and Health Professions | 7 | 7% |
| Agricultural and Biological Sciences | 6 | 6% |
| Immunology and Microbiology | 5 | 5% |
| Veterinary Science and Veterinary Medicine | 4 | 4% |
| Other | 14 | 14% |
| Unknown | 25 | 25% |