| Title |
Inhibition of Firefly Luciferase by General Anesthetics: Effect on In Vitro and In Vivo Bioluminescence Imaging
|
|---|---|
| Published in |
PLOS ONE, January 2012
|
| DOI | 10.1371/journal.pone.0030061 |
| Pubmed ID | |
| Authors |
Marleen Keyaerts, Isabel Remory, Vicky Caveliers, Karine Breckpot, Tomas J. Bos, Jan Poelaert, Axel Bossuyt, Tony Lahoutte |
| Abstract |
Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery. However, general anesthetics have been described as important inhibitors of the luciferase enzyme reaction. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 1% |
| France | 1 | 1% |
| Australia | 1 | 1% |
| Romania | 1 | 1% |
| Japan | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 82 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 26% |
| Student > Ph. D. Student | 20 | 23% |
| Student > Master | 7 | 8% |
| Student > Doctoral Student | 7 | 8% |
| Student > Bachelor | 7 | 8% |
| Other | 19 | 22% |
| Unknown | 5 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 33% |
| Biochemistry, Genetics and Molecular Biology | 13 | 15% |
| Medicine and Dentistry | 12 | 14% |
| Immunology and Microbiology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 17 | 19% |
| Unknown | 9 | 10% |