Title |
Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection
|
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Published in |
PLOS ONE, January 2012
|
DOI | 10.1371/journal.pone.0029770 |
Pubmed ID | |
Authors |
Michael G. Schrauder, Reiner Strick, Rüdiger Schulz-Wendtland, Pamela L. Strissel, Laura Kahmann, Christian R. Loehberg, Michael P. Lux, Sebastian M. Jud, Arndt Hartmann, Alexander Hein, Christian M. Bayer, Mayada R. Bani, Swetlana Richter, Boris R. Adamietz, Evelyn Wenkel, Claudia Rauh, Matthias W. Beckmann, Peter A. Fasching |
Abstract |
MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules with relevance as regulators of gene expression thereby affecting crucial processes in cancer development. MiRNAs offer great potential as biomarkers for cancer detection due to their remarkable stability in blood and their characteristic expression in many different diseases. We investigated whether microarray-based miRNA profiling on whole blood could discriminate between early stage breast cancer patients and healthy controls. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Belgium | 4 | 2% |
United Kingdom | 3 | 1% |
India | 1 | <1% |
New Caledonia | 1 | <1% |
Belarus | 1 | <1% |
Denmark | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 204 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 54 | 25% |
Student > Ph. D. Student | 43 | 20% |
Student > Master | 24 | 11% |
Student > Bachelor | 22 | 10% |
Professor > Associate Professor | 12 | 6% |
Other | 41 | 19% |
Unknown | 21 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 59 | 27% |
Medicine and Dentistry | 53 | 24% |
Biochemistry, Genetics and Molecular Biology | 35 | 16% |
Engineering | 10 | 5% |
Computer Science | 8 | 4% |
Other | 21 | 10% |
Unknown | 31 | 14% |