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Promoting Long-Term Survival of Insulin-Producing Cell Grafts That Differentiate from Adipose Tissue-Derived Stem Cells to Cure Type 1 Diabetes

Overview of attention for article published in PLOS ONE, December 2011
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Title
Promoting Long-Term Survival of Insulin-Producing Cell Grafts That Differentiate from Adipose Tissue-Derived Stem Cells to Cure Type 1 Diabetes
Published in
PLOS ONE, December 2011
DOI 10.1371/journal.pone.0029706
Pubmed ID
Authors

Shuzi Zhang, Hehua Dai, Ni Wan, Yolonda Moore, Zhenhua Dai

Abstract

Insulin-producing cell clusters (IPCCs) have recently been generated in vitro from adipose tissue-derived stem cells (ASCs) to circumvent islet shortage. However, it is unknown how long they can survive upon transplantation, whether they are eventually rejected by recipients, and how their long-term survival can be induced to permanently cure type 1 diabetes. IPCC graft survival is critical for their clinical application and this issue must be systematically addressed prior to their in-depth clinical trials.

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Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 23%
Student > Master 6 15%
Student > Bachelor 4 10%
Professor > Associate Professor 4 10%
Professor 3 8%
Other 8 20%
Unknown 6 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 33%
Medicine and Dentistry 8 20%
Biochemistry, Genetics and Molecular Biology 4 10%
Engineering 2 5%
Chemical Engineering 1 3%
Other 5 13%
Unknown 7 18%