| Title |
Vitamin D3 Deficiency Differentially Affects Functional and Disease Outcomes in the G93A Mouse Model of Amyotrophic Lateral Sclerosis
|
|---|---|
| Published in |
PLOS ONE, December 2011
|
| DOI | 10.1371/journal.pone.0029354 |
| Pubmed ID | |
| Authors |
Jesse A. Solomon, Alexandro Gianforcaro, Mazen J. Hamadeh |
| Abstract |
Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by motor neuron death in the central nervous system. Vitamin D supplementation increases antioxidant activity, reduces inflammation and improves motor neuron survival. We have previously demonstrated that vitamin D(3) supplementation at 10× the adequate intake improves functional outcomes in a mouse model of ALS. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 2% |
| Korea, Republic of | 1 | 1% |
| Unknown | 85 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 23 | 26% |
| Student > Master | 13 | 15% |
| Researcher | 10 | 11% |
| Student > Postgraduate | 8 | 9% |
| Student > Ph. D. Student | 7 | 8% |
| Other | 10 | 11% |
| Unknown | 17 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 26% |
| Agricultural and Biological Sciences | 17 | 19% |
| Sports and Recreations | 11 | 13% |
| Biochemistry, Genetics and Molecular Biology | 7 | 8% |
| Neuroscience | 5 | 6% |
| Other | 10 | 11% |
| Unknown | 15 | 17% |