| Title |
Recombinant Probiotic Expressing Listeria Adhesion Protein Attenuates Listeria monocytogenes Virulence In Vitro
|
|---|---|
| Published in |
PLOS ONE, January 2012
|
| DOI | 10.1371/journal.pone.0029277 |
| Pubmed ID | |
| Authors |
Ok Kyung Koo, Mary Anne Roshni Amalaradjou, Arun K. Bhunia |
| Abstract |
Listeria monocytogenes, an intracellular foodborne pathogen, infects immunocompromised hosts. The primary route of transmission is through contaminated food. In the gastrointestinal tract, it traverses the epithelial barrier through intracellular or paracellular routes. Strategies to prevent L. monocytogenes entry can potentially minimize infection in high-risk populations. Listeria adhesion protein (LAP) aids L. monocytogenes in crossing epithelial barriers via the paracellular route. The use of recombinant probiotic bacteria expressing LAP would aid targeted clearance of Listeria from the gut and protect high-risk populations from infection. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Malaysia | 1 | 1% |
| Italy | 1 | 1% |
| Unknown | 86 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 27% |
| Student > Bachelor | 11 | 12% |
| Student > Master | 10 | 11% |
| Researcher | 9 | 10% |
| Other | 5 | 6% |
| Other | 10 | 11% |
| Unknown | 20 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 33% |
| Biochemistry, Genetics and Molecular Biology | 15 | 17% |
| Immunology and Microbiology | 9 | 10% |
| Medicine and Dentistry | 7 | 8% |
| Nursing and Health Professions | 3 | 3% |
| Other | 5 | 6% |
| Unknown | 21 | 24% |