Title |
Omentum-Wrapped Scaffold with Longitudinally Oriented Micro-Channels Promotes Axonal Regeneration and Motor Functional Recovery in Rats
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Published in |
PLOS ONE, December 2011
|
DOI | 10.1371/journal.pone.0029184 |
Pubmed ID | |
Authors |
Yong-Guang Zhang, Jing-Hui Huang, Xue-Yu Hu, Qing-Song Sheng, Wei Zhao, Zhuo-Jing Luo |
Abstract |
Tissue-engineered nerve scaffolds hold great potential in bridging large peripheral nerve defects. However, insufficient vascularization of nerve scaffolds limited neural tissues survival and regeneration, which hampered the successful implantation and clinical application of nerve scaffolds. The omentum possesses a high vascularization capacity and enhances regeneration and maturation of tissues and constructs to which it is applied. However, combined application of nerve scaffolds and omentum on axonal regeneration and functional recovery in the treatment of large peripheral nerve defects has rarely been investigated thus far. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 23% |
Student > Bachelor | 6 | 20% |
Student > Ph. D. Student | 4 | 13% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Other | 4 | 13% |
Unknown | 4 | 13% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 7 | 23% |
Medicine and Dentistry | 7 | 23% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 7% |
Chemistry | 2 | 7% |
Engineering | 2 | 7% |
Other | 3 | 10% |
Unknown | 7 | 23% |