Title |
The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia
|
---|---|
Published in |
PLOS ONE, December 2011
|
DOI | 10.1371/journal.pone.0029167 |
Pubmed ID | |
Authors |
Nikolai L. Chepelev, Joshua D. Bennitz, Ting Huang, Skye McBride, William G. Willmore |
Abstract |
Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs) located in their promoter regions. Despite its potential importance in human health, the mechanisms controlling Nrf1 have not been addressed fully. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Romania | 1 | 2% |
Slovenia | 1 | 2% |
South Africa | 1 | 2% |
Unknown | 61 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 17% |
Student > Master | 11 | 17% |
Student > Ph. D. Student | 10 | 15% |
Student > Bachelor | 8 | 12% |
Professor > Associate Professor | 5 | 8% |
Other | 12 | 18% |
Unknown | 8 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 27 | 42% |
Biochemistry, Genetics and Molecular Biology | 14 | 22% |
Medicine and Dentistry | 6 | 9% |
Chemistry | 5 | 8% |
Neuroscience | 2 | 3% |
Other | 3 | 5% |
Unknown | 8 | 12% |