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The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia

Overview of attention for article published in PLOS ONE, December 2011
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Title
The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia
Published in
PLOS ONE, December 2011
DOI 10.1371/journal.pone.0029167
Pubmed ID
Authors

Nikolai L. Chepelev, Joshua D. Bennitz, Ting Huang, Skye McBride, William G. Willmore

Abstract

Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs) located in their promoter regions. Despite its potential importance in human health, the mechanisms controlling Nrf1 have not been addressed fully.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Romania 1 2%
Slovenia 1 2%
South Africa 1 2%
Unknown 61 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 17%
Student > Master 11 17%
Student > Ph. D. Student 10 15%
Student > Bachelor 8 12%
Professor > Associate Professor 5 8%
Other 12 18%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 42%
Biochemistry, Genetics and Molecular Biology 14 22%
Medicine and Dentistry 6 9%
Chemistry 5 8%
Neuroscience 2 3%
Other 3 5%
Unknown 8 12%