| Title |
Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor Death
|
|---|---|
| Published in |
PLOS ONE, December 2011
|
| DOI | 10.1371/journal.pone.0028791 |
| Pubmed ID | |
| Authors |
Marie-Noëlle Delyfer, Wolfgang Raffelsberger, David Mercier, Jean-François Korobelnik, Alain Gaudric, David G. Charteris, Ramin Tadayoni, Florence Metge, Georges Caputo, Pierre-Olivier Barale, Raymond Ripp, Jean-Denis Muller, Olivier Poch, José-Alain Sahel, Thierry Léveillard |
| Abstract |
Retinal detachment often leads to a severe and permanent loss of vision and its therapeutic management remains to this day exclusively surgical. We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment in order to identify new potential pharmacological targets that could be used in combination with surgery to further improve final outcome. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 3% |
| Unknown | 39 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 28% |
| Student > Ph. D. Student | 9 | 23% |
| Other | 7 | 18% |
| Student > Doctoral Student | 2 | 5% |
| Student > Master | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 5 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 35% |
| Agricultural and Biological Sciences | 9 | 23% |
| Neuroscience | 4 | 10% |
| Biochemistry, Genetics and Molecular Biology | 3 | 8% |
| Materials Science | 2 | 5% |
| Other | 2 | 5% |
| Unknown | 6 | 15% |