| Title |
Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model
|
|---|---|
| Published in |
PLOS ONE, November 2011
|
| DOI | 10.1371/journal.pone.0028077 |
| Pubmed ID | |
| Authors |
Christopher K. McCann, Whitfield B. Growdon, Kashmira Kulkarni-Datar, Michael D. Curley, Anne M. Friel, Jennifer L. Proctor, Hana Sheikh, Igor Deyneko, Jeanne A. Ferguson, Vinod Vathipadiekal, Michael J. Birrer, Darrell R. Borger, Gayatry Mohapatra, Lawrence R. Zukerberg, Rosemary Foster, John R. MacDougall, Bo R. Rueda |
| Abstract |
Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, basal cell, small cell lung, pancreatic, prostate and ovarian. This investigation was designed to determine if inhibition of this pathway could inhibit serous ovarian cancer growth. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 39 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 27% |
| Student > Bachelor | 10 | 24% |
| Researcher | 7 | 17% |
| Professor > Associate Professor | 4 | 10% |
| Student > Master | 2 | 5% |
| Other | 2 | 5% |
| Unknown | 5 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 37% |
| Agricultural and Biological Sciences | 12 | 29% |
| Biochemistry, Genetics and Molecular Biology | 5 | 12% |
| Chemistry | 1 | 2% |
| Engineering | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 7 | 17% |