| Title |
Defects of Protein Phosphatase 2A Causes Corticosteroid Insensitivity in Severe Asthma
|
|---|---|
| Published in |
PLOS ONE, December 2011
|
| DOI | 10.1371/journal.pone.0027627 |
| Pubmed ID | |
| Authors |
Yoshiki Kobayashi, Nicolas Mercado, Peter J. Barnes, Kazuhiro Ito |
| Abstract |
Corticosteroid insensitivity is a major barrier of treatment for some chronic inflammatory diseases, such as severe asthma, but the molecular mechanism of the insensitivity has not been fully elucidated. The object of this study is to investigate the role of protein phosphate 2A (PP2A), a serine/threonine phosphatase, on corticosteroid sensitivity in severe asthma. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Argentina | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 45 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 19% |
| Researcher | 8 | 17% |
| Student > Bachelor | 6 | 13% |
| Student > Postgraduate | 5 | 11% |
| Student > Master | 5 | 11% |
| Other | 10 | 21% |
| Unknown | 4 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 30% |
| Medicine and Dentistry | 13 | 28% |
| Biochemistry, Genetics and Molecular Biology | 7 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 11% |
| Immunology and Microbiology | 3 | 6% |
| Other | 2 | 4% |
| Unknown | 3 | 6% |