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Identification of LZAP as a New Candidate Tumor Suppressor in Hepatocellular Carcinoma

Overview of attention for article published in PLOS ONE, October 2011
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Title
Identification of LZAP as a New Candidate Tumor Suppressor in Hepatocellular Carcinoma
Published in
PLOS ONE, October 2011
DOI 10.1371/journal.pone.0026608
Pubmed ID
Authors

Jing-jing Zhao, Ke Pan, Jian-jun Li, Yi-bing Chen, Ju-gao Chen, Lin Lv, Dan-dan Wang, Qiu-zhong Pan, Min-shan Chen, Jian-chuan Xia

Abstract

LZAP was isolated as a binding protein of the Cdk5 activator p35. LZAP has been highly conserved during evolution and has been shown to function as a tumor suppressor in various cancers. This study aimed to investigate LZAP expression and its prognostic value in hepatocellular carcinoma (HCC). Meanwhile, the function of LZAP in hepatocarcinogenesis was further investigated in cell culture models and mouse models.

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The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 19%
Researcher 3 14%
Student > Bachelor 3 14%
Student > Postgraduate 2 10%
Student > Master 2 10%
Other 2 10%
Unknown 5 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 43%
Biochemistry, Genetics and Molecular Biology 2 10%
Medicine and Dentistry 2 10%
Immunology and Microbiology 1 5%
Chemistry 1 5%
Other 0 0%
Unknown 6 29%