Title |
Identification of LZAP as a New Candidate Tumor Suppressor in Hepatocellular Carcinoma
|
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Published in |
PLOS ONE, October 2011
|
DOI | 10.1371/journal.pone.0026608 |
Pubmed ID | |
Authors |
Jing-jing Zhao, Ke Pan, Jian-jun Li, Yi-bing Chen, Ju-gao Chen, Lin Lv, Dan-dan Wang, Qiu-zhong Pan, Min-shan Chen, Jian-chuan Xia |
Abstract |
LZAP was isolated as a binding protein of the Cdk5 activator p35. LZAP has been highly conserved during evolution and has been shown to function as a tumor suppressor in various cancers. This study aimed to investigate LZAP expression and its prognostic value in hepatocellular carcinoma (HCC). Meanwhile, the function of LZAP in hepatocarcinogenesis was further investigated in cell culture models and mouse models. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 19% |
Researcher | 3 | 14% |
Student > Bachelor | 3 | 14% |
Student > Postgraduate | 2 | 10% |
Student > Master | 2 | 10% |
Other | 2 | 10% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 43% |
Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Medicine and Dentistry | 2 | 10% |
Immunology and Microbiology | 1 | 5% |
Chemistry | 1 | 5% |
Other | 0 | 0% |
Unknown | 6 | 29% |