| Title |
Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
|
|---|---|
| Published in |
PLOS ONE, October 2011
|
| DOI | 10.1371/journal.pone.0026358 |
| Pubmed ID | |
| Authors |
Øystein Fluge, Ove Bruland, Kristin Risa, Anette Storstein, Einar K. Kristoffersen, Dipak Sapkota, Halvor Næss, Olav Dahl, Harald Nyland, Olav Mella |
| Abstract |
Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion using the anti-CD20 antibody Rituximab, which demonstrated significant clinical response in three CFS patients. |
X Demographics
The data shown below were collected from the profiles of 158 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Norway | 11 | 7% |
| United States | 11 | 7% |
| United Kingdom | 11 | 7% |
| Netherlands | 4 | 3% |
| Canada | 3 | 2% |
| Australia | 2 | 1% |
| Switzerland | 1 | <1% |
| Austria | 1 | <1% |
| Unknown | 114 | 72% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 148 | 94% |
| Practitioners (doctors, other healthcare professionals) | 9 | 6% |
| Science communicators (journalists, bloggers, editors) | 5 | 3% |
| Scientists | 3 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 233 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Norway | 2 | <1% |
| United Kingdom | 2 | <1% |
| Australia | 1 | <1% |
| Netherlands | 1 | <1% |
| Israel | 1 | <1% |
| Unknown | 221 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 53 | 23% |
| Student > Ph. D. Student | 32 | 14% |
| Other | 25 | 11% |
| Student > Master | 22 | 9% |
| Student > Doctoral Student | 17 | 7% |
| Other | 49 | 21% |
| Unknown | 35 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 80 | 34% |
| Agricultural and Biological Sciences | 31 | 13% |
| Biochemistry, Genetics and Molecular Biology | 14 | 6% |
| Immunology and Microbiology | 12 | 5% |
| Nursing and Health Professions | 11 | 5% |
| Other | 48 | 21% |
| Unknown | 37 | 16% |