Title |
RANTES/CCL5 and Risk for Coronary Events: Results from the MONICA/KORA Augsburg Case-Cohort, Athero-Express and CARDIoGRAM Studies
|
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Published in |
PLOS ONE, December 2011
|
DOI | 10.1371/journal.pone.0025734 |
Pubmed ID | |
Authors |
Christian Herder, Wouter Peeters, Thomas Illig, Jens Baumert, Dominique P V de Kleijn, Frans L Moll, Ulrike Poschen, Norman Klopp, Martina Müller-Nurasyid, Michael Roden, Michael Preuss, Mahir Karakas, Christa Meisinger, Barbara Thorand, Gerard Pasterkamp, Wolfgang Koenig, Themistocles L Assimes, Panos Deloukas, Jeanette Erdmann, Hilma Holm, Sekar Kathiresan, Inke R König, Ruth McPherson, Muredach P Reilly, Robert Roberts, Nilesh J Samani, Heribert Schunkert, Alexandre F R Stewart |
Abstract |
The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice, whereas less is known in humans. We hypothesised that its relevance for atherosclerosis should be reflected by associations between CCL5 gene variants, RANTES serum concentrations and protein levels in atherosclerotic plaques and risk for coronary events. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Netherlands | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 1% |
Unknown | 79 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 20% |
Professor | 12 | 15% |
Student > Ph. D. Student | 11 | 14% |
Student > Master | 8 | 10% |
Professor > Associate Professor | 6 | 8% |
Other | 11 | 14% |
Unknown | 16 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 35% |
Agricultural and Biological Sciences | 10 | 13% |
Biochemistry, Genetics and Molecular Biology | 8 | 10% |
Immunology and Microbiology | 3 | 4% |
Engineering | 2 | 3% |
Other | 7 | 9% |
Unknown | 22 | 28% |