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Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score

Overview of attention for article published in PLOS ONE, November 2011
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Title
Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score
Published in
PLOS ONE, November 2011
DOI 10.1371/journal.pone.0025665
Pubmed ID
Authors

Alessandro Cozzi-Lepri, Mattia C. F. Prosperi, Jesper Kjær, David Dunn, Roger Paredes, Caroline A. Sabin, Jens D. Lundgren, Andrew N. Phillips, Deenan Pillay, for the EuroSIDA and the United Kingdom CHIC/United Kingdom HDRD Studies

Abstract

The question of whether a score for a specific antiretroviral (e.g. lopinavir/r in this analysis) that improves prediction of viral load response given by existing expert-based interpretation systems (IS) could be derived from analyzing the correlation between genotypic data and virological response using statistical methods remains largely unanswered.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 1 3%
Tanzania, United Republic of 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 5 17%
Researcher 5 17%
Student > Master 4 14%
Student > Ph. D. Student 4 14%
Other 3 10%
Other 2 7%
Unknown 6 21%
Readers by discipline Count As %
Medicine and Dentistry 7 24%
Agricultural and Biological Sciences 4 14%
Nursing and Health Professions 4 14%
Biochemistry, Genetics and Molecular Biology 2 7%
Social Sciences 2 7%
Other 4 14%
Unknown 6 21%