| Title |
Identification of Rothia Bacteria as Gluten-Degrading Natural Colonizers of the Upper Gastro-Intestinal Tract
|
|---|---|
| Published in |
PLOS ONE, September 2011
|
| DOI | 10.1371/journal.pone.0024455 |
| Pubmed ID | |
| Authors |
Maram Zamakhchari, Guoxian Wei, Floyd Dewhirst, Jaeseop Lee, Detlef Schuppan, Frank G. Oppenheim, Eva J. Helmerhorst |
| Abstract |
Gluten proteins, prominent constituents of barley, wheat and rye, cause celiac disease in genetically predisposed subjects. Gluten is notoriously difficult to digest by mammalian proteolytic enzymes and the protease-resistant domains contain multiple immunogenic epitopes. The aim of this study was to identify novel sources of gluten-digesting microbial enzymes from the upper gastro-intestinal tract with the potential to neutralize gluten epitopes. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 44% |
| United Kingdom | 2 | 11% |
| Australia | 1 | 6% |
| United Arab Emirates | 1 | 6% |
| Unknown | 6 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 61% |
| Scientists | 3 | 17% |
| Practitioners (doctors, other healthcare professionals) | 3 | 17% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Arab Emirates | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 144 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 21% |
| Student > Bachelor | 23 | 16% |
| Researcher | 18 | 12% |
| Student > Master | 16 | 11% |
| Student > Doctoral Student | 10 | 7% |
| Other | 22 | 15% |
| Unknown | 27 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 39 | 27% |
| Biochemistry, Genetics and Molecular Biology | 28 | 19% |
| Medicine and Dentistry | 18 | 12% |
| Immunology and Microbiology | 11 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 16 | 11% |
| Unknown | 30 | 21% |