Title |
Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death
|
---|---|
Published in |
PLOS ONE, September 2011
|
DOI | 10.1371/journal.pone.0024361 |
Pubmed ID | |
Authors |
Meghana Tare, Rohan M. Modi, Jaison J. Nainaparampil, Oorvashi Roy Puli, Shimpi Bedi, Pedro Fernandez-Funez, Madhuri Kango-Singh, Amit Singh |
Abstract |
Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular alterations that trigger neuronal cell death. However, the exact mechanisms leading to cell death are not clearly understood. |
Mendeley readers
The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Switzerland | 1 | 2% |
Unknown | 40 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 21% |
Researcher | 9 | 21% |
Student > Bachelor | 7 | 17% |
Student > Master | 5 | 12% |
Professor | 4 | 10% |
Other | 1 | 2% |
Unknown | 7 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 16 | 38% |
Medicine and Dentistry | 7 | 17% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Psychology | 2 | 5% |
Neuroscience | 2 | 5% |
Other | 3 | 7% |
Unknown | 7 | 17% |