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Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death

Overview of attention for article published in PLOS ONE, September 2011
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Title
Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death
Published in
PLOS ONE, September 2011
DOI 10.1371/journal.pone.0024361
Pubmed ID
Authors

Meghana Tare, Rohan M. Modi, Jaison J. Nainaparampil, Oorvashi Roy Puli, Shimpi Bedi, Pedro Fernandez-Funez, Madhuri Kango-Singh, Amit Singh

Abstract

Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular alterations that trigger neuronal cell death. However, the exact mechanisms leading to cell death are not clearly understood.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Switzerland 1 2%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 21%
Researcher 9 21%
Student > Bachelor 7 17%
Student > Master 5 12%
Professor 4 10%
Other 1 2%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 38%
Medicine and Dentistry 7 17%
Biochemistry, Genetics and Molecular Biology 5 12%
Psychology 2 5%
Neuroscience 2 5%
Other 3 7%
Unknown 7 17%