Title |
RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design
|
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Published in |
PLOS ONE, August 2011
|
DOI | 10.1371/journal.pone.0024109 |
Pubmed ID | |
Authors |
Po-Ssu Huang, Yih-En Andrew Ban, Florian Richter, Ingemar Andre, Robert Vernon, William R. Schief, David Baker |
Abstract |
We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 7 | 2% |
United Kingdom | 2 | <1% |
Canada | 2 | <1% |
India | 1 | <1% |
Germany | 1 | <1% |
Switzerland | 1 | <1% |
Korea, Republic of | 1 | <1% |
Unknown | 377 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 112 | 29% |
Researcher | 82 | 21% |
Student > Master | 38 | 10% |
Student > Bachelor | 30 | 8% |
Student > Postgraduate | 21 | 5% |
Other | 48 | 12% |
Unknown | 61 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 108 | 28% |
Agricultural and Biological Sciences | 106 | 27% |
Chemistry | 45 | 11% |
Computer Science | 21 | 5% |
Engineering | 11 | 3% |
Other | 32 | 8% |
Unknown | 69 | 18% |