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Osteopontin Enhances the Expression and Activity of MMP-2 via the SDF-1/CXCR4 Axis in Hepatocellular Carcinoma Cell Lines

Overview of attention for article published in PLOS ONE, August 2011
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Title
Osteopontin Enhances the Expression and Activity of MMP-2 via the SDF-1/CXCR4 Axis in Hepatocellular Carcinoma Cell Lines
Published in
PLOS ONE, August 2011
DOI 10.1371/journal.pone.0023831
Pubmed ID
Authors

Rihua Zhang, Xiaolin Pan, Zuhu Huang, Georg F. Weber, Guoxin Zhang

Abstract

Osteopontin, SDF-1α, and MMP-2 are important secreted molecules involved in the pathophysiology of human hepatocellular carcinoma (HCC). This study investigates the effect of the SDF-1α/CXCR4 axis on expression and activity of MMP-2 induced by osteopontin.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
Germany 1 2%
Unknown 48 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 28%
Student > Ph. D. Student 10 20%
Student > Bachelor 5 10%
Student > Master 4 8%
Student > Postgraduate 3 6%
Other 7 14%
Unknown 7 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 34%
Medicine and Dentistry 13 26%
Biochemistry, Genetics and Molecular Biology 8 16%
Neuroscience 1 2%
Unknown 11 22%