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Efficient Removal of Platelets from Peripheral Blood Progenitor Cell Products Using a Novel Micro-Chip Based Acoustophoretic Platform

Overview of attention for article published in PLOS ONE, August 2011
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Title
Efficient Removal of Platelets from Peripheral Blood Progenitor Cell Products Using a Novel Micro-Chip Based Acoustophoretic Platform
Published in
PLOS ONE, August 2011
DOI 10.1371/journal.pone.0023074
Pubmed ID
Authors

Josefina Dykes, Andreas Lenshof, Ing-Britt Åstrand-Grundström, Thomas Laurell, Stefan Scheding

Abstract

Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
New Zealand 1 <1%
Sweden 1 <1%
Unknown 98 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 28%
Student > Master 22 22%
Researcher 14 14%
Student > Bachelor 7 7%
Student > Doctoral Student 6 6%
Other 11 11%
Unknown 13 13%
Readers by discipline Count As %
Engineering 47 46%
Agricultural and Biological Sciences 12 12%
Medicine and Dentistry 6 6%
Physics and Astronomy 5 5%
Chemical Engineering 5 5%
Other 12 12%
Unknown 15 15%