Title |
ENZO: A Web Tool for Derivation and Evaluation of Kinetic Models of Enzyme Catalyzed Reactions
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Published in |
PLOS ONE, July 2011
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DOI | 10.1371/journal.pone.0022265 |
Pubmed ID | |
Authors |
Staš Bevc, Janez Konc, Jure Stojan, Milan Hodošček, Matej Penca, Matej Praprotnik, Dušanka Janežič |
Abstract |
We describe a web tool ENZO (Enzyme Kinetics), a graphical interface for building kinetic models of enzyme catalyzed reactions. ENZO automatically generates the corresponding differential equations from a stipulated enzyme reaction scheme. These differential equations are processed by a numerical solver and a regression algorithm which fits the coefficients of differential equations to experimentally observed time course curves. ENZO allows rapid evaluation of rival reaction schemes and can be used for routine tests in enzyme kinetics. It is freely available as a web tool, at http://enzo.cmm.ki.si. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Portugal | 2 | 2% |
Unknown | 83 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 26 | 30% |
Student > Ph. D. Student | 20 | 23% |
Student > Master | 11 | 13% |
Professor | 4 | 5% |
Student > Bachelor | 4 | 5% |
Other | 15 | 17% |
Unknown | 7 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 28 | 32% |
Biochemistry, Genetics and Molecular Biology | 11 | 13% |
Chemistry | 9 | 10% |
Engineering | 8 | 9% |
Computer Science | 3 | 3% |
Other | 18 | 21% |
Unknown | 10 | 11% |