| Title |
Anticancer Activities of Six Selected Natural Compounds of Some Cameroonian Medicinal Plants
|
|---|---|
| Published in |
PLOS ONE, August 2011
|
| DOI | 10.1371/journal.pone.0021762 |
| Pubmed ID | |
| Authors |
Victor Kuete, Hippolyte K. Wabo, Kenneth O. Eyong, Michel T. Feussi, Benjamin Wiench, Benjamin Krusche, Pierre Tane, Gabriel N. Folefoc, Thomas Efferth |
| Abstract |
Natural products are well recognized as sources of drugs in several human ailments. In the present work, we carried out a preliminary screening of six natural compounds, xanthone V(1) (1); 2-acetylfuro-1,4-naphthoquinone (2); physcion (3); bisvismiaquinone (4); vismiaquinone (5); 1,8-dihydroxy-3-geranyloxy-6-methylanthraquinone (6) against MiaPaCa-2 pancreatic and CCRF-CEM leukemia cells and their multidrug-resistant subline, CEM/ADR5000. Compounds 1 and 2 were then tested in several other cancer cells and their possible mode of action were investigated. |
Mendeley readers
The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Cameroon | 1 | <1% |
| India | 1 | <1% |
| Brunei Darussalam | 1 | <1% |
| Unknown | 117 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 26 | 21% |
| Student > Ph. D. Student | 24 | 20% |
| Student > Doctoral Student | 11 | 9% |
| Student > Bachelor | 8 | 7% |
| Researcher | 6 | 5% |
| Other | 17 | 14% |
| Unknown | 29 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 21% |
| Chemistry | 14 | 12% |
| Biochemistry, Genetics and Molecular Biology | 14 | 12% |
| Medicine and Dentistry | 12 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 7% |
| Other | 9 | 7% |
| Unknown | 38 | 31% |