| Title |
β2-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D
|
|---|---|
| Published in |
PLOS ONE, May 2011
|
| DOI | 10.1371/journal.pone.0020000 |
| Pubmed ID | |
| Authors |
Thomas Trian, Janette K. Burgess, Kyoko Niimi, Lyn M. Moir, Qi Ge, Patrick Berger, Stephen B. Liggett, Judith L. Black, Brian G. Oliver |
| Abstract |
Asthma is associated with airway narrowing in response to bronchoconstricting stimuli and increased airway smooth muscle (ASM) mass. In addition, some studies have suggested impaired β-agonist induced ASM relaxation in asthmatics, but the mechanism is not known. |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 47 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 19% |
| Researcher | 8 | 17% |
| Student > Master | 7 | 15% |
| Student > Bachelor | 5 | 11% |
| Other | 3 | 6% |
| Other | 5 | 11% |
| Unknown | 10 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 26% |
| Medicine and Dentistry | 10 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 9% |
| Biochemistry, Genetics and Molecular Biology | 4 | 9% |
| Environmental Science | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 12 | 26% |