| Title |
Structural and Histone Binding Ability Characterizations of Human PWWP Domains
|
|---|---|
| Published in |
PLOS ONE, June 2011
|
| DOI | 10.1371/journal.pone.0018919 |
| Pubmed ID | |
| Authors |
Hong Wu, Hong Zeng, Robert Lam, Wolfram Tempel, Maria F. Amaya, Chao Xu, Ludmila Dombrovski, Wei Qiu, Yanming Wang, Jinrong Min |
| Abstract |
The PWWP domain was first identified as a structural motif of 100-130 amino acids in the WHSC1 protein and predicted to be a protein-protein interaction domain. It belongs to the Tudor domain 'Royal Family', which consists of Tudor, chromodomain, MBT and PWWP domains. While Tudor, chromodomain and MBT domains have long been known to bind methylated histones, PWWP was shown to exhibit histone binding ability only until recently. |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 2% |
| United States | 2 | 1% |
| Denmark | 2 | 1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 175 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 30% |
| Researcher | 30 | 16% |
| Student > Master | 19 | 10% |
| Student > Bachelor | 16 | 9% |
| Student > Doctoral Student | 10 | 5% |
| Other | 24 | 13% |
| Unknown | 30 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 31% |
| Biochemistry, Genetics and Molecular Biology | 48 | 26% |
| Chemistry | 22 | 12% |
| Medicine and Dentistry | 7 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 13 | 7% |
| Unknown | 32 | 17% |