| Title |
Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria
|
|---|---|
| Published in |
PLOS ONE, April 2011
|
| DOI | 10.1371/journal.pone.0018127 |
| Pubmed ID | |
| Authors |
Yiannis C. Fiamegos, Panagiotis L. Kastritis, Vassiliki Exarchou, Haley Han, Alexandre M. J. J. Bonvin, Jacques Vervoort, Kim Lewis, Michael R. Hamblin, George P. Tegos |
| Abstract |
Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated as potential alternative treatments. One plausible antimicrobial alternative could be the combination of conventional antimicrobial agents/antibiotics with small molecules which block multidrug efflux systems known as efflux pump inhibitors. Bioassay-driven purification and structural determination of compounds from plant sources have yielded a number of pump inhibitors which acted against gram positive bacteria. |
Mendeley readers
The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | <1% |
| Japan | 2 | <1% |
| Brazil | 1 | <1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 204 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 32 | 15% |
| Student > Ph. D. Student | 31 | 15% |
| Researcher | 25 | 12% |
| Student > Bachelor | 23 | 11% |
| Student > Doctoral Student | 18 | 8% |
| Other | 39 | 18% |
| Unknown | 44 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 27% |
| Biochemistry, Genetics and Molecular Biology | 21 | 10% |
| Chemistry | 18 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 7% |
| Immunology and Microbiology | 14 | 7% |
| Other | 33 | 16% |
| Unknown | 54 | 25% |